Customization: | Available |
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Function: | Anti Wrinkle Lip Enhancement |
Theory: | Injectable |
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PROFHILO® is based on stabilsed hybrid cooperative complex, and it is the pioneer of BIOREMODELLING. It is the first product developed with NAHYCO® technology, a unique and innovative thermal production process, 100% free of chemical stabilising agents, patented by IBSA.
PROFHILO® is indicated for TISSUE REMODELING AND IMPROVEMENT IN SKIN LAXITY of face, neck, and décolletage. PROFHILO® promotes the restoration of firmness, tone and elasticity of tissues in an authentic way, leading to a DYNAMIC MULTILEVEL REMODELLING of the extracellular matrix in terms of elasticity and support, as well as maintaining and promoting the normal vitality of Fibroblasts, Keratinocytes and Adipocytes.
Unique characteristics of the product are: natural HA with a duration comparable to a low cross-linked gel, high HA concentration (64mg/2ml), high manageability, extensive spreadability, low viscosity, no BDDE or other chemical agents, and low inflammatory response.
(P.S: the package way of Profhilo has some difference sometimes .)
Profhilo® is not a dermal filler or biorevitaliser - Profhilo® has opened up a new injectable category - bioremodeling.
Thermal cross-linking changes the character and behavior of the HA resulting in the formation of co-operative hybrid complexes which modulate the tissues. This is also the explanation for the different biological behavior with respect to H-HA and L-HA alone. One of the main advantages is longevity. Hybrid cooperative complexes have proven to be very stable with natural hyaluronidase (BTH) digestion when compared to H-HA, widely used in biorevitalisation products, or L-HA alone resulting in the long-lasting release and the dual action of the two HA components. This dual action is ideal for remodeling skin laxity.
How does Profhilo work?
Profhilo is the first BDDE-free injectable Hyaluronic Acid for hydrating skin and treating skin laxity.
With one of the highest concentrations of HA in the market (64mg/2cc), the stabilised HA lasts in the skin for about 28 days.
Profhilo works because of 2 types of hyaluronic acid: L-HA and H-HA. This hybrid of HA allows hyaluronic acid to be released slowly and lasts longer allowing bioremodeling to take place.
L-HA as a hybrid complex is released slowly and hydrates your skin, providing the Hydro effect.
H-HA provides a stable HA architecture in the dermis that allows volumetric replacement, giving the Lift effect.
During this time, the slow release of HA kickstarts stimulation of 4 different types of collagen and elastin.
Histologically, the expression levels of type I and type III collagen and type IV and VII collagen in keratinocytes are increased.
Profilo treatment is considered a bioremodelling therapy. This unique stabilized hybrid cooperative HA complex has different biological properties when compared to monotherapy with either High or Low molecular weight HAs. The resistance to enzymatic degradation, slow release action and biocompatibility properties makes it different from the standard HAs in today's market.
The slow release action of Profhilo treatment provides hydration at the epidermal layer and enhances volume within the dermal architecture. There is an up-regulation of the 4 main types of collagen. There is an increased expression of type I and III collagen in fibroblasts and type IV and VII in keratinocytes. In addition, elastin and natural HAs within the skin are stimulated. This multimodal effect increases hydration, elasticity and lifting effect of the skin.
Can Profhilo be used for other Indications?